Nandan Haloi

Nandan Haloi

Marie Curie Postdoctoral Fellow

KTH Royal Institute of Technology

Biography

Dr. Haloi is driven by a fundamental question: how do biomolecules work at the atomic level to power life? Combining molecular simulations, machine learning, and experimental data like cryo-EM and small-angle scattering, he unravels the intricate motions of proteins and their interactions with drugs. He is currently a Marie Skłodowska-Curie Actions Postdoctoral Fellow at KTH Royal Institute of Technology. His work has been recognized with prestigious awards and featured in top journals, reflecting his commitment to advancing science and mentoring future researchers.

Interests
  • Membrane Protein Dynamics.
  • Drug-Protein Interactions.
  • Molecular Simulations.
  • Machine Learning.
  • Integrative Modeling.
Education
  • PhD in Biophysics and Quantitative Biology (PI- Emad Tajkhorshid), 2021

    University of Illinois at Urbana-Champaign, Illinois, USA

  • BTech in Chemical Science and Technology, 2016

    Indian Institute of Technology Guwahati, Assam, India

Major Grants

Publications

Discovering cryptic pocket opening and binding of a stimulant derivative in a vestibular site of the 5-HT3A receptor
Discovering cryptic pocket opening and binding of a stimulant derivative in a vestibular site of the 5-HT3A receptor
Cryo-EM ligand building using generative AI and molecular dynamics
Cryo-EM ligand building using generative AI and molecular dynamics
Modeling cryo-EM structures in alternative states with generative AI and density-guided simulations
Modeling cryo-EM structures in alternative states with generative AI and density-guided simulations
Adaptive sampling-based structural prediction reveals opening of a GABAA receptor through the αβ interface
Adaptive sampling-based structural prediction reveals opening of a GABAA receptor through the αβ interface
Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold
Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold